CBD and the Interaction with Endocannabinoid System
If you have ever searched for hemp oil online, you may have noticed the mention of the term ‘endocannabinoid system’. The endocannabinoid system plays a crucial role in how hemp oil affects the body. Contrary to popular belief, the basic working mechanism of cannabinoids on the human body is quite simple.
Cannabinoids found in the cannabis plant acts on the endocannabinoid system, which regulates the digestion, pressure, pain modulation, sleep etc. While this may sound simple, the interaction between the dedicated receptors and cannabinoids is complicated.
Thus, in this post, we will be focusing on one of the most important compounds of cannabis i.e. cannabidiol. There have been many research studies on the impact of CBD oil on a variety of body parts. The studies also confirm the direct impact of cannabidiol on the receptors of an endocannabinoid system.
If you are not familiar with the endogenous or endocannabinoid system, it simply refers to a collection of cellular receptors along with corresponding molecules present in different parts of the body i.e. in the organs, the brain, glands, connective tissues, and immune cells.
Even though the endocannabinoid system is responsible for performing specific tasks in every tissue, the primary goal is to maintain an optimal balance or homeostasis within the body.
Due to the endocannabinoid system’s ability to maintain homeostasis in the body, it is the most critical physiological system for our health.
Endocannabinoid System and CBD
As per several scientific studies, the endocannabinoid system not only responds to the endocannabinoid that is present within the body, but it also responds to different external cannabinoids, such as phytocannabinoid cannabidiol or CBD oil.
Therefore, the consumption of CBD oil for pain can help reduce the symptoms of a number of health conditions, including multiple sclerosis, epilepsy, depression, chronic inflammation, rheumatoid arthritis, diabetes, anxiety as well as opioid withdrawal.
How Does CBD Oil Work?
CBD acts upon different CBD receptors (CB1 and CB2) present throughout the body and can produce a number of potentially positive results. However, cannabidiol does not directly bind to any of the receptors but rather indirectly influences them. This may include TRPV1 receptor activation that controls different important functions, such as body temperature, pain perception, and inflammation.
When CBD stimulates the endocannabinoid system, it promotes homeostasis, decreases inflammation and reduces pain sensation.
However CBD oil lacks psychotropic activity with regard to therapeutic applications. To further prove the effective interaction between CBD and endocannabinoid system, a study was conducted to explore the interaction between the CBD1 and ECS in hippocampal cells of a cultured rat.
During investigation, researchers learned that the endocannabinoid system also responds and recognizes cannabinoids from different external sources, including CBD oil.
The endocannabinoid system helps cells communicate with each other and with the organs, tissues and the larger systems in the body. There is also further evidence that supports ECS as a bridge between the mind and body.
Cannabinoids helps regulate the internal and cellular homeostasis. In addition, it can also influence the relationship of an individual with the external environment.
The effect of CBD oil on the endocannabinoid system along with its impact on different areas of the body shows that it can be used for treating a number of medical conditions. Since CBD or CBD oil inhibits the negative effects of THC, it is likely that the administration of the two could be a lot more advantageous than supplementing with THC alone.